Phenotypic plasticity of fat synthesis
Our research focuses primarily on the study of lipid metabolism in parasitic insects. These insects were initially thought to have lost (and regained) the ability for fat synthesis during the course of evolution. Our latest findings revealed that fat synthesis was not lost in the parasitic wasp Leptopilina heterotoma, a Drosophila parasitoid, but that this species evolved plasticity in fat synthesis. When wasps develop in a fat-poor environment fat synthesis will be switched on during adult life, but when development takes place in a fat-rich environment fat synthesis will be completely shut off. It is exceptional that fat synthesis can be completely shut off, because these wasps are still feeding on a superfluous supply of sugars. Our current aim is to get more insight into the molecular bases of plasticity in fat synthesis.
The work in our lab is funded by: